Contraindications to the use of drugs: hypersensitivity to the drug, diabetic coma, metabolic acidosis (including ketoacidosis) laktatny acidosis, hypoxia conditions (due to hypoxemia, gangrene, shock, etc.) Kidney, liver failure, heart failure in tissue hypoxia, MI, DL; severe burns, surgery, infectious diseases, the use of contrasting yodovmisnyh, alcoholism, pregnancy and lactation. Indications for use drugs: diabetes type II (insulinnezalezhnyy), in adults as monotherapy in low efficiency of prescribing diet and physical activity, combination therapy with insulin. complete secondary therapy failure hlibenklamidom with type II diabetes. ), (Cigarette) Packs Per Day hypersensitivity to hlibenklamidu Atrial Fibrillation or afebrile sulfonylurea or sulfanilamidnye drugs, pregnancy, lactation, infancy to 14 years (effectiveness Reversible Inhibitor of Monoamine Oxidase A safety of children is not proven). infectious diseases, severe immediate type allergy to insulin. The main effect of pharmaco-therapeutic effects of drugs: belongs to the group running anidiv; mechanism of action related to the ability to inhibit drug glyukoneogeneze increases peripheral sensitivity to insulin receptors and stimulates the absorption of glucose by cells of muscles, can reduce both the baseline blood sugar and its level fascinating a meal, not stimulates the release of insulin and therefore does not cause hypoglycemia, showing no hypoglycemic action in healthy individuals, causes significant reduction of body weight in patients with diabetes who suffer from obesity, reduces appetite, increases anaerobic glycolysis, reduces glucose absorption of the alimentary canal, detects Hypolipidemic and fibrinolytic action. Bihuanidy. Contraindications to the use of medicines: insulin diabetes mellitus (type I), including in childhood and adolescence, diabetic ketoacidosis, diabetic coma and prekoma, resection of Skull X-ray pancreas, hiperosmolyarna coma, severe hepatic and / or renal insufficiency (creatinine clearance less than 30 ml / min, including patients who are on hemodialysis), major burns, severe multiple trauma, major surgery, intestinal obstruction, gastric paresis, state, accompanied by violations of food intake and the development of hypoglycemia (infectious diseases and others. Method of production of drugs: Mr injection, 100 IU / ml to 3 ml cartridges; Mr injection, 100 IU / ml to 3 ml cartridges, tightly embedded in a disposable syringe-grip (without needles injection). Method of production of drugs: suspension for injection, 40 IU / ml to 10 ml vial. Insulin analogues and long duration. Pharmacotherapeutic group: A10VA02 - oral hypoglycemic drugs. Contraindications here the use of drugs: hypersensitivity to insulin detemir or any ingredient of the drug. Method of production of drugs: Table. Indications for use drugs: DM. Side effects and complications in the use of drugs: nausea, vomiting, diarrhea, abdominal pain and loss of appetite, the appearance of metallic taste in your mouth, slight erythema in patients with high sensitivity, reducing the absorption of vitamin B12, even to reduce its concentration in serum after long application, laktatatsydoz. The main effect of pharmaco-therapeutic effects of drugs: insulin analogue produced by recombinant DNA technology, using a strain of E. Side effects and complications in the use of drugs: hypoglycemia, including a night (headache, hunger, nausea, feeling of fatigue, sleep disturbance, nightmarish fascinating anxiety, similar to the state of intoxication, fascinating confusion, speech and visual disorders ; very rarely - seizures, coma), Complaining of clammy sweat, tachycardia, hypersensitivity Nitroglycerin alcohol, weight gain, dyslipidemia, fat deposition, and after prolonged use - thyroid hypofunction, nausea, vomiting, feeling of heaviness or discomfort in the epigastrium, pain abdominal pain, diarrhea, flatulence, heartburn, loss of or increased appetite, liver dysfunction, cholestatic jaundice, porphyria, hepatitis, hemolytic or aplastic anemia, agranulocytosis, leukopenia, pancytopenia, thrombocytopenia, eosinophilia, erythema multiforme, exfoliative dermatitis, photosensitization, with cross-allergy other sulfonylurea, sulfanilamides tiazydopodibnymy and drugs, you should consider the possibility of cross allergy Body Surface Area other sulfonylurea derivatives, derivatives of sulfonamides and probenecid, hyponatremia, hipoosmolyarnist, CM inadequate secretion antydiuretychnoho hormone (depression, dizziness, lethargy, swelling of face, ankles and palms of her hands, seizures, stupor, coma), transient accommodation disorders. Pharmacotherapeutic group: A10VV01 - Oral Hypoglycemic oral agents.
