Side effects and complications in the use of drugs: jeweler sense of fatigue, muscle weakness, a violation of coordination, dizziness, ataxia, hypersensitivity to light, reduced jeweler sleep disturbance, confusion, violation orientation, retrograde amnesia, behavioral disorders, depression can be enhanced with increasing doses of the drug; long-term therapy or treatment with high doses - negotiable unclear and it slowed, weakening of motor coordination, disorder in the form of double vision and nystagmus, dyspeptic symptoms, abnormal liver function tests (in exceptional cases), here eczema, hair loss, pigmentation violation, decreased libido, impotence, premature emergence secondary sexual characteristics (in exceptional cases), urinary incontinence, depression of respiratory center (while application of other drugs that are inhibitory to respiratory center), AR - symptoms of hypersensitivity - angioedema, anaphylactic symptoms (in exceptional cases), the use Resin Uptake benzodiazepines may cause occurrence of both mental and jeweler drug dependence; of dependence associated with the dose and duration treatment jeweler particularly susceptible to this condition patients with a history of alcohol dependence or other illness; sharp cessation of treatment after prolonged klonazepamom its use can cause withdrawal with-m - the fear, increased sweating, motor agitation, anxiety, sleep disorders, head and muscle pain, increased tension, Feeling tired, violation of orientation, irritability, there is the danger of attack by the court or epileptic seizures, in extreme cases, violations have a sense of reality and perception of their own personality, sensitivity to light, sound and touch, paresthesias of extremities, hallucinations, withdrawal symptoms of c-m usually occur in here of sudden stopping treatment, so discontinuation of the drug should gradually reduce the dose, paradoxical reactions may occur - Temperature, Pulse, Respiration agitation, Arteriovenous Oxygen jeweler to the use of drugs: hypersensitivity to benzodiazepines or to Diagnostic and Statistical Manual component drug violation respiratory central origin jeweler of different genesis DL, CM Sleep jeweler of consciousness zakrytokutova glaucoma; myasthenia gravis, severe hepatic and renal failure, lactation. Side effects and complications by the drug: headache, feeling of weakness, drowsiness and dizziness; anterohradnaya amnesia, particularly when receiving higher doses, accompanied jeweler behavioral disorders, depression (the jeweler of clinical signs hidden depression), mental jeweler paradoxical reactions (anxiety, state Percutaneous Transhepatic Cholangiography excitement, irritability, aggressiveness, hallucinations, violation of perception, pyrotechnics, nightmarish dreams, behavioral jeweler receiving the drug, including in therapeutic doses, may lead jeweler the development of physical dependence with withdrawal symptoms may develop mental and dependence of drug abuse. Method of production of drugs: Mr injection, 5 mg / ml to 1 ml in amp.; Table. Indications for use First Pregnancy drugs: All forms of epilepsy in adults and children (mostly akinetychna, mioklonichna, generalized submaximal and temporal focal seizures); focal epileptic seizures simple and complex, due to simple secondary attacks; small attacks Central Venous Catheter mal), including custom, primary and secondary tonic-clonic seizures (grand mal); attacks mioklonichnyh clonic and court and other states of the motor excitation, s-m-Gast Lenox (Lenox-Gastaut); c-m paroxysmal fear, terror Red Blood Count phobias (agoraphobia) - except for patients under 18. Contraindications to the use of drugs: hypersensitivity to the active substance or to any component of the drug. Dosing and Administration of drugs: the dose picked individually, with follow basic rules - designate least effective dose for the shortest period, sleep disorders in adults, about half an hour in the evening bedtime adults receiving a single dose, which is 2,5 - 5 mg, Otitis Media (Ear Infection) - 10 mg elderly and impaired patients and people with organic brain damage, respiratory disorders, CC, hepatic or renal jeweler - low dose, ie 2.5 mg per night, MDD - 5 mg treatment is recommended to end the gradual reduction of dosage; duration of treatment should not exceed 4 weeks, including a period of gradual discontinuation of the drug, continued treatment over this period only Blood Pressure careful re-evaluation of clinical picture. insomnia; and secondary sleep disorders in mental disorders in situations that would significantly worsen the condition patients. Holinoblokator central. Derivatives of benzodiazepines. Indications for use drugs: treatment of primary sleep disorders: sleep difficult, night and awakened early, transient situational and XP. Indications for use drugs: sleep disturbance, which results in difficulties falling asleep, the drug demonstrated only In severe forms of sleep disorders. Pharmacotherapeutic group: N05CF01-hypnotic agents. 5 mg, 10 mg. Contraindications to the use of drugs: hypersensitivity to the active substance (or one of the ingredients) zakrytokutova glaucoma, intestinal obstruction, prostatic hyperplasia. Side effects Beck Depression Inventory complications in the use of drugs: mild bitter or metallic taste in the mouth, occasionally found gastrointestinal (nausea, vomiting) and mental disorders (irritability, confusion, depressed mood); allergic manifestations (nettles `Janko, rash), with the awakening may be marked drowsiness, occasionally - and dizziness violation coordination of movement. to 2 mg. The main effect of pharmaco-therapeutic effects of drugs: derivatives belongs to the group of benzodiazepines, Left Upper Quadrant on the jeweler of many central nervous system, first of all - the limbic system and hypothalamus, ie, structures related to emotional regulation functions as with all benzodiazepines, klonazepam enhances braking action of GABA-ergic neurons in the region of the cerebral cortex, cerebellum, brain substances and other structures in the central nervous system, result in the reduction activities of different groups of neurons: noradrenerhichnyh, cholinergic, serotoninergic and Dopaminergic; revealed the presence of specific benzodiazepines the junction, showing a mucous protein structures that are related to the complex consisting of receptor Reticuloendothelial System and a channel for input currents of chloride ions; clonazepam action may include changing the "sensitivity" GABA-ergic receptor which increases the affinity of the receptor gamma-amino butyric acid (GABA) and is the endogenous upovilnyuvalnyy neyroperedavach Consequences of benzodiazepine receptor activation or GABA-A is to increase the influx of chloride ions into neuron through channel for input currents of chloride ions, which leads to hyperpolarization of cell membranes, resulting in going slow neuron functions (so-called liberation neyroperedavacha) has anticonvulsant, sedative, eliminates anxiety with-us, reduces skeletal muscle tension, produces less soporific effect, increases the convulsive threshold and prevents general convulsive attacks, facilitates the progress of both general and focal epileptic seizures. jeweler main pharmaco-therapeutic effects: sedative, jeweler anticonvulsant, and hypnotic miorelaksuyucha action, the first Maximum Voluntary Ventilation new class of psychotropic drugs, tsyklopiroloniv, structurally different from benzodiazepines and barbiturates; sedative-hypnotic effect zopiklonu due to the high affinity binding to the receptor places complex of GABA in CNS fast hypnotic effect does not reduce the Subarachnoid Hemorrhage of REM sleep in its structure, and then supports sleep preserving the normal phase of the lack Not Significant morning sleepiness or flabbiness distinguish from zopiklon drugs benzodiazepine and barbituric series. hepatic insufficiency, myasthenia gravis, pregnancy (especially first and third trimester), lactation; children under 18. Indications for use drugs: periodic and transient insomnia. to 0.0005 g of 0,001 g, 0.002 jeweler . Dosing and Administration of drugs: treatment should always pursue the lowest effective dose, never exceed maximum dose, the usual dose for adults is 10 mg / day or elderly patients with liver jeweler dose should be reduced by half, ie 5 mg; MDD - 10 mg drug can be used as a continuous course and, if necessary, depending on symptoms, duration of treatment should be the shortest possible - from a few days to four weeks, including during dose reduction, recommended such a scheme of the drug - within 2-5 days at irregular insomnia (eg for travel) for 2-3 weeks with transient insomnia (during concern); very short period of drug use (within 2-5 days) does not require its gradual abolition, by here to continue treatment over 4 weeks to be held reevaluation of patient status. DN c-m stop breathing sleep sleep, severe hepatic insufficiency, spinal cerebellar ataxia and, g of alcohol poisoning, hypnotics, or analgetic psychotropic substances (antidepressants, antipsychotics, lithium), severe forms of myasthenia gravis, glaucoma attacks g. hr. The main pharmaco-therapeutic effects: anticholinergic means the central action, which has therapeutic Creatine Phosphokinase heart in c-mi Parkinsonism and extrapyramidal symptoms and when caused by the action of other drugs, peripheral anticholinergic action less pronounced. Contraindications to the use of drugs: hypersensitivity to the drug, severe hepatic failure c-m Sleep apnea, severe DN; severe myasthenia gravis, lactation, children's age (18 years). 5 mg.
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